Contact Information
University of Illinois
3406 IGB
1206 W Gregory Dr
Urbana, IL 61801
Research Areas
Biography
I work on evolutionary and systems biology and carry out computational modeling of complex biological systems ranging from genome evolution and biomolecular networks to ecosystem dynamics. I am a statistical physicist by training so that in my research I often use physics-based modeling techniques. I particularly love simple-yet-rich "bottom down" models.
Education
B.S., 1989, Moscow Institute of Physics and Technology and Kapitza Institute for Physical Problems, Moscow (Physics and Math)
M.S., 1992, Moscow Institute of Physics and Technology and Landau Institute for Theoretical Physics, Moscow (Physics and Applied Math)
Ph.D., 1996, SUNY at Stony Brook (Physics)
Awards and Honors
Presidential Early Career Award for Scientists and Engineers (PECASE), 2004
Additional Campus Affiliations
Professor, Bioengineering
Affiliate, Carl R. Woese Institute for Genomic Biology
Professor, Physics
Professor, National Center for Supercomputing Applications (NCSA)
Affiliate, Personalized Nutrition Initiative, Carl R. Woese Institute for Genomic Biology
External Links
Recent Publications
Rivera-Cardona, J., Mahajan, T., Thayer, E. A., Kakuturu, N. R., Teo, Q. W., Lederer, J., Rowland, E. F., Heimburger, K., Sun, J., McDonald, C. A., Mickelson, C. K., Langlois, R. A., Wu, N. C., Milenkovic, O., Maslov, S., & Brooke, C. B. (2026). Intrinsic OASL expression governs heterogeneity in interferon induction during influenza A virus infection. Proceedings of the National Academy of Sciences of the United States of America, 123(1), Article e2509560123. https://doi.org/10.1073/pnas.2509560123
Shirguppe, S., Gapinske, M., Swami, D., Shenouda, K., Miskalis, A., Gosstola, N., Del Bosque Siller, D., Guerra, I., Acharya, P., Joulani, D., Szkwarek, M. G., Nambiar, A., Bhattacharjee, A., Dangi, A. S., Odle, N., Nathan, G. E., Elias, G., Stilger, M., Winter, J., ... Perez-Pinera, P. (2026). In vivo CRISPR base editing for treatment of Huntington’s disease. Nature biomedical engineering. Advance online publication. https://doi.org/10.1038/s41551-026-01747-y
Thayer, E. A., Shipman, G., Rivera-Cardona, J., Mahajan, T., Teo, Q. W., Paez, J. S., Lederer, J., Chen, J., Wu, N. C. H., Maslov, S., & Brooke, C. B. (Accepted/In press). Single-cell heterogeneity in interferon induction potential is heritable and governed by variation in cell state. Cell Systems, Article 101676. https://doi.org/10.1016/j.cels.2026.101676
Wang, Z., Fu, Y., Goyal, A., & Maslov, S. (2026). Fitness advantage of sequential metabolic strategies emerges from community interactions in strongly fluctuating environments. PloS one, 22(5), Article e1014277. https://doi.org/10.1371/journal.pcbi.1014277
Wang, T., George, A. B., & Maslov, S. (2026). Higher-order interactions in auxotroph communities enhance their resilience to resource fluctuations. Cell Systems, 17(3), Article 101491. https://doi.org/10.1016/j.cels.2025.101491