Profile picture for Sergei Maslov

Contact Information

Woese Institute for Genomic Biology
University of Illinois
3406 IGB
1206 W Gregory Dr
Urbana, IL 61801
Professor

Biography

I work on evolutionary and systems biology and carry out computational modeling of complex biological systems ranging from genome evolution and biomolecular networks to ecosystem dynamics. I am a statistical physicist by training so that in my research I often use physics-based modeling techniques. I particularly love simple-yet-rich "bottom down" models.

Education

B.S., 1989, Moscow Institute of Physics and Technology and Kapitza Institute for Physical Problems, Moscow (Physics and Math)
M.S., 1992, Moscow Institute of Physics and Technology and Landau Institute for Theoretical Physics, Moscow (Physics and Applied Math)
Ph.D., 1996, SUNY at Stony Brook (Physics)

Awards and Honors

Presidential Early Career Award for Scientists and Engineers (PECASE), 2004

Additional Campus Affiliations

Professor, Bioengineering
Affiliate, Carl R. Woese Institute for Genomic Biology
Professor, Physics
Professor, National Center for Supercomputing Applications (NCSA)
Affiliate, Personalized Nutrition Initiative, Carl R. Woese Institute for Genomic Biology

Recent Publications

Rivera-Cardona, J., Mahajan, T., Thayer, E. A., Kakuturu, N. R., Teo, Q. W., Lederer, J., Rowland, E. F., Heimburger, K., Sun, J., McDonald, C. A., Mickelson, C. K., Langlois, R. A., Wu, N. C., Milenkovic, O., Maslov, S., & Brooke, C. B. (2026). Intrinsic OASL expression governs heterogeneity in interferon induction during influenza A virus infection. Proceedings of the National Academy of Sciences of the United States of America, 123(1), Article e2509560123. https://doi.org/10.1073/pnas.2509560123

Wang, T., George, A. B., & Maslov, S. (2026). Higher-order interactions in auxotroph communities enhance their resilience to resource fluctuations. Cell Systems, 17(3), Article 101491. https://doi.org/10.1016/j.cels.2025.101491

Mahajan, T., & Maslov, S. (2025). Coarse-grained model of serial dilution dynamics in synthetic human gut microbiome. PLoS computational biology, 21(7 JULY), Article e1013222. https://doi.org/10.1371/journal.pcbi.1013222

Wang, T., Holscher, H. D., Maslov, S., Hu, F. B., Weiss, S. T., & Liu, Y. Y. (2025). Predicting metabolite response to dietary intervention using deep learning. Nature communications, 16(1), Article 815. https://doi.org/10.1038/s41467-025-56165-6

Dubinkina, V., Bhogale, S., Hsieh, P. H., Dibaeinia, P., Nambiar, A., Maslov, S., Yoshikuni, Y., & Sinha, S. (2024). A transcriptomic atlas of acute stress response to low pH in multiple Issatchenkia orientalis strains. Microbiology Spectrum, 12(1). https://doi.org/10.1128/spectrum.02536-23

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