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Deborah E Leckband

Leckband

Professor

leckband@illinois.edu

127 RAL, MC-712
Office: (217) 244-0793
Lab: (217) 244-2007
Fax: (217) 333-5052

Department of Chemical and Biomolecular Engineering
University of Illinois
127 RAL Box C-3
600 S Mathews Ave
Urbana, IL 61801

Lab Page

Curriculum Vita

Molecular Mechanisms of Cell Adhesion; Cell Engineering; Molecular force movements; structure; proteins; electrostatics; biomembranes

Research Interests


The BioInterfaces and Cellular Mechanics Group is determining how cells sense and respond to the environment. A major current focus is on mechanotransduction and the conversion of mechanical information into intracellular signaling and molecular cascades that control such cell functions as stem cell differentiation or metastasis. Our multidisciplinary approach engineers cell microenvironments using surface chemistry and microfabrication. We use multiscale biophysical and biochemical approaches to investigate cell adhesion and mechanotransduction, and in turn identify engineering design rules for controlling cell and tissue functions.

Education

B.S., 1982, Humboldt State University
Ph.D., 1988, Cornell University
Postdoct., 1988-1992, Massachusetts Institute of Technology and University of California, Santa Barbara

Awards

American Association for the Advancement of Science Fellow 2005
University Scholar, 2001-2004
National Science Foundation CAREER Award, 1995-1999
National Institutes of Health FIRST Award, 1993-1998