Functional and structural characterization of protein enzymes involved in RNA modification and editing, site-specific RNA cleavage, and RNA repair
The major research in our laboratory focuses on studies of RNA-protein interaction. We are particularly interested in protein enzymes acting on RNA. Using integrated approaches of chemical biology, biochemistry, and structural biology, we strive to provide insight into RNA substrate recognition and reaction mechanisms of the protein enzymes. The research can further be divided into three specific areas that are related to one another.
B.S./M.S., 1986, Nankai University, PRC
Ph.D., 1995, University of Washington
Postdoc., 1996-99, Harvard University